HYALURONIC ACID2018-08-04T18:25:40+00:00


Hyaluronic acid (HA) is naturally occurring in human body, especially in the eyes and joint fluids. It is a very popular nutraceutical supplement for joint disorders. It is also popular for its application on dermal tissues for wound healing, burns, skin ulcers, and as a moisturizer.

Basically, in joints, hyaluronic acid acts as a cushion and as a lubricant. However, it plays multifaceted role in regulating various biological processes and maintaining homeostasis in the body. A significant volume of research exhibited the biomedical implications of HA in skin repairment, wound healing, tissue regeneration, anti-inflammation, and immunomodulation. A thorough analysis of the literature revealed that HA based formulations (e.g., gels, creams, autologous graft, thin sheets, soaked gauze, gauze pad, tincture, injection) have shown remarkable efficacy in treating a wide range of inflammatory skin diseases. The safety, tolerability, and efficacy of HA have also been well-documented for treatment of various types of joint disease including knee osteoarthritis, joint osteoarthritis, canine osteoarthritis, and meniscal swelling. A remarkable improvement in chondrocyte density, territorial matrix appearance, reconstitution of superficial amorphous layer of the cartilage, collagen remodelling, and regeneration of meniscus have also been evident in patients treated with HA. Overall, application/administration of HA is a promising pharmacotherapeutic regimen for treatment of inflammatory skin and joint diseases.


  • Supports healthy joints*
  • Promotes healthy skin*

Hyaluronic acid powder

Hyaluronic acid has been used as a joint health promoting ingredients for awhile and has been studied in depth:

T.C. Laurent, University of Uppsala, Sweden

Evaluation of HA after surgery
Bioconti. Prague University, Czech Republic

Evaluation of hyaluronic acid in people
B. Sardi, Ohtsuma University, Tokyo, Japan

Int J Biol Macromol 116
Chen LH et al., (2018) 572-584.

Clin Transl Med
Bowman S et al., 2018 Feb 16;7(1):6. doi: 10.1186/s40169-017-0180-3.

Altman R et al., 2018 Feb 1:1947603517749919. doi: 10.1177/1947603517749919.

J Biol Regul Homeost Agents
Papalia R et al., 2017 Dec 27;31(4 Suppl 2):91-102.

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